The aim of this project was to investigate comprehensively the in vitro activity and mechanism of action of tea tree oil and components against fungi. Fungi are significant human pathogens, causing common superficial infections like tinea or athlete's foot and vaginal thrush.
This report covers studies on the in vitro activity of both tea tree oil and its components against yeasts, dermatophytes and other filamentous fungi. Activity was assessed by standard in vitro susceptibility and time-kill assays. This report also describes several different studies on the mechanism of action of tea tree oil against yeasts, in particular C. albicans.